Haplotype-Specific DNA Methylation
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FEN1
hits 7
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1
rs102275
chr11:61557802-61557803
genes 17
GWAS disease/phenotype 7
rs102275
LD Block:
chr11:61285952-61729063
Genes:
AHNAK
BEST1
C11orf0
C11orf10
C11orf9
DAGLA
FADS1
FADS2
FADS3
FEN1
FTH1
INCENP
RAB3IL1
SCGB1D1
SCGB2A1
SCGB2A2
SYT7
GWAS Disease/Phenotype:
Crohns disease
Metabolite levels
Oleic acid (18:1n-9) plasma levels
Palmitoleic acid (16:1n-7) plasma levels
Phospholipid levels (plasma)
Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid)
Stearic acid (18:0) plasma levels
2
rs4246215
chr11:61564298-61564299
genes 4
GWAS disease/phenotype 3
rs4246215
LD Block:
chr11:61285952-61729063
Genes:
C11orf9
FADS1
FADS2
FEN1
GWAS Disease/Phenotype:
Inflammatory bowel disease
Phospholipid levels (plasma)
Platelet counts
3
rs174541
chr11:61565907-61565908
genes 4
GWAS disease/phenotype 1
rs174541
LD Block:
chr11:61285952-61729063
Genes:
FADS1
FADS2
FADS3
FEN1
GWAS Disease/Phenotype:
Metabolite levels
4
rs174547
chr11:61570782-61570783
genes 16
GWAS disease/phenotype 11
rs174547
LD Block:
chr11:61285952-61729063
Genes:
BEST1
C11orf10
C11orf9
DAGLA
FADS1
FADS2
FADS3
FEN1
FTH1
INCENP
RAB3IL
RAB3IL1
SCGB1D1
SCGB1D2
SCGB2A1
SYT7
GWAS Disease/Phenotype:
HDL cholesterol
Lipid metabolism phenotypes
Metabolic traits
Metabolite levels
Phospholipid levels (plasma)
Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid)
Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid)
Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid)
Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid)
Resting heart rate
Triglycerides
5
rs174550
chr11:61571477-61571478
genes 16
GWAS disease/phenotype 5
rs174550
LD Block:
chr11:61285952-61729063
Genes:
BEST1
C11orf10
C11orf9
DAGLA
FADS1
FADS2
FADS3
FEN1
FTH1
INCENP
RAB3IL
RAB3IL1
SCGB1D1
SCGB1D2
SCGB2A1
SYT7
GWAS Disease/Phenotype:
Fasting glucose-related traits
Fasting glucose-related traits (interaction with BMI)
Phospholipid levels (plasma)
Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid)
Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid)
6
rs174555
chr11:61579759-61579760
genes 10
GWAS disease/phenotype 1
rs174555
LD Block:
chr11:61285952-61729063
Genes:
BEST1
C11orf10
C11orf9
DAGLA
FADS1
FADS2
FADS3
FEN1
FTH1
RAB3IL1
GWAS Disease/Phenotype:
Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid)
7
rs2727270
chr11:61603236-61603237
genes 15
GWAS disease/phenotype 1
rs2727270
LD Block:
chr11:61285952-61729063
Genes:
BEST1
C11orf10
C11orf9
DAGLA
FADS1
FADS2
FADS3
FEN1
FTH1
INCENP
RAB3IL
SCGB1D1
SCGB1D2
SCGB2A1
SYT7
GWAS Disease/Phenotype:
Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid)
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