Haplotype-Specific DNA Methylation
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Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid)

hits  3

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1  rs174547  chr11:61570782-61570783
genes 16 GWAS disease/phenotype 11
rs174547

LD Block:  chr11:61285952-61729063

Genes:

  • BEST1
  • C11orf10
  • C11orf9
  • DAGLA
  • FADS1
  • FADS2
  • FADS3
  • FEN1
  • FTH1
  • INCENP
  • RAB3IL
  • RAB3IL1
  • SCGB1D1
  • SCGB1D2
  • SCGB2A1
  • SYT7

GWAS Disease/Phenotype:

  • HDL cholesterol
  • Lipid metabolism phenotypes
  • Metabolic traits
  • Metabolite levels
  • Phospholipid levels (plasma)
  • Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid)
  • Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid)
  • Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid)
  • Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid)
  • Resting heart rate
  • Triglycerides

2  rs4985155  chr16:15129458-15129459
genes 8 GWAS disease/phenotype 3
rs4985155

LD Block:  chr16:14471419-15883490

Genes:

  • C16orf45
  • KIAA0430
  • MYH11
  • NDEI
  • NTAN1
  • PARN
  • PDXDC1
  • RRN3

GWAS Disease/Phenotype:

  • Bone mineral density
  • Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid)
  • Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid)

3  rs16966952  chr16:15135942-15135943
genes 8 GWAS disease/phenotype 3
rs16966952

LD Block:  chr16:14471419-15883490

Genes:

  • C16orf45
  • KIAA0430
  • MYH11
  • NDEI
  • NTAN1
  • PARN
  • PDXDC1
  • RRN3

GWAS Disease/Phenotype:

  • Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid)
  • Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid)
  • Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid)

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